Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS)
نویسندگان
چکیده
1 Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA 2 Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA 3 Department of Neurology, Ghent University Hospital, Ghent, B.9000, Belgium 4 Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA 5 Department of Neurology, Mayo Clinic College of Medicine, Jacksonville, FL 32224, USA
منابع مشابه
A case of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) in East Asia.
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) syndrome is a clinically and radiologically distinct pontine-predominant perivascular neuroinflammation showing T lymphocyte infiltration. It is assumed to have an autoimmune or other inflammatory mediated pathogenesis. We report the first known case of CLIPPERS in East Asia, characterized b...
متن کاملExpanding phenotype of CLIPPERS indicates it to be a disease or a syndrome?
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a newly named condition of pontine-centric inflammatory disorder. 1) The cardinal feature of the disease is punctate gadolinium enhancement " peppering " the pons on magnetic resonance imaging (MRI). The unique MRI features
متن کامل[CLIPPERS (chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids)].
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) has been recently identified as an inflammatory central nervous system (CNS) disorder. Punctate and curvilinear gadolinium enhancement (peppering) the pons is a characteristic magnetic resonance imaging (MRI) feature of CLIPPERS. Pathogenesis of this disorder remains unknown. A specific seru...
متن کاملEffective antituberculous therapy in a patient with CLIPPERS: New insights into CLIPPERS pathogenesis
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a brainstem relapsing-remitting inflammatory disease. To date, no treatment besides corticosteroids has been shown to be effective to treat relapses. We report a patient with CLIPPERS initially misdiagnosed with CNS tuberculosis who presented with brainstem attacks responsive to antituber...
متن کاملChronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids with a Significant Elevation of β-2 Microglobulin Levels
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a relapsing-remitting disorder for which steroid administration is a key to control the progression. CLIPPERS can exhibit radiological features similar to malignant lymphoma, whose diagnosis is confounded by prior steroid administration. We report a case of CLIPPERS accompanied by abnorma...
متن کاملChronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) with Limbic Encephalitis
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory central nervous system disorder that mainly involves in the brainstem, basal ganglia and cerebellum. We herein report the case of a patient with CLIPPERS, which was diagnosed based on the clinical and radiological features. After initially responded to steroid treatment, t...
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تاریخ انتشار 2010